Acclimatizing with Acetazolamide

Acclimatizing Taxonomic Semantics for Hierarchical Content Classification

Hierarchical models have been shown to be effective in content classification. However, we observe through empirical study that the performance of a hierarchical model varies with given taxonomies; even a semantically sound taxonomy has potential to change its structure for better classification. By scrutinizing typical cases, we elucidate why a given semantics-based hierarchy does not work wel...

High-altitude corneal oedema associated with acetazolamide.

Brain SPECT imaging with acetazolamide challenge.

The patient was a 69-y-old man who, 37 d earlier, had a 4-d-long evolving onset of headache, dizziness, acute personality changes, visual changes, and weakness. Unspecified imaging was obtained at an outside facility, and he was diagnosed with an intracerebral stenosis. Subsequently, he was given aspirin and clopidogrel (Plavix; Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership) and told ...

Acetazolamide: Treatment of Psychogenic Polydipsia

We are reporting a case of psychogenic polydipsia from a State of Ohio psychiatric hospital. The patient has a known five-year history of psychogenic polydipsia with recurrent hyponatremia and has been diagnosed with schizoaffective disorder bipolar type 1, according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria, for the past two decades. There was...

Acetazolamide-based fungal chitinase inhibitors

Chitin is an essential structural component of the fungal cell wall. Chitinases are thought to be important for fungal cell wall remodelling, and inhibition of these enzymes has been proposed as a potential strategy for development of novel anti-fungals. The fungal pathogen Aspergillus fumigatus possesses two distinct multi-gene chitinase families. Here we explore acetazolamide as a chemical sc...